Genetics of Aging, Age-related Disease, and Longevity
Our long-term research goal is to investigate the genetic components of aging and aging-related disease using functional genomics approaches.
We focus on the identification of gene sequence variation, i.e. single nucleotide polymorphisms (SNPs), in candidate genes and the assessment of their potential functional impact on aging-related phenotypes.
Ongoing Projects
Genetics of Human Longevity (Ashkenazi Jewish Centenarian cohorts)
Genetics of Aging (Longitudinal Study of Aging cohorts)
Genetics of Aging Related Disease (Coronary Artery Diseases, Alzheimer’s Disease, etc.)
Epigenetics of Cellular Senescence and Human Aging
Role of Small Non-Coding RNA in Human Aging and Longevity
Role of Mitochondrial nuclear gene variants in Longevity
Role of Systemic Rejuvenating Factors in Human Longevity
